|
Symbol Name ID |
Dnmt1
DNA methyltransferase 1 MGI:94912 |
| Darker colors indicate more annotations |
| Human Phenotypes | Spasticity |
Decreased number of peripheral myelinated nerve fibers |
Cerebral atrophy |
Cerebellar atrophy |
Ataxia |
Cataplexy |
Depression |
Irritability |
Psychosis |
Hypnagogic hallucination |
Apathy |
Polyphagia |
Hyperactivity |
Impulsivity |
Delirium |
Memory impairment |
Dementia |
Narcolepsy |
Excessive daytime somnolence |
Abnormal rapid eye movement sleep |
Sleep paralysis |
Hyperreflexia |
Primitive reflex |
Hyporeflexia |
Sensory neuropathy |
| Disease(s) Associated with DNMT1 | |||||||||||||||||||||||||
| autosomal dominant cerebellar ataxia, deafness and narcolepsy | |||||||||||||||||||||||||
| Graves' disease | |||||||||||||||||||||||||
| hereditary sensory neuropathy type 1E |
| Mouse Phenotypes | increased neuron apoptosis |
abnormal neural tube morphology |
open neural tube |
decreased neuron number |
decreased neuronal stem cell self-renewal |
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| Availability | Mouse Genotype | |||||
| Dnmt1tm1Enl/Dnmt1tm1Enl | ||||||
| Dnmt1tm2Enl/Dnmt1tm2Enl | ||||||
| Dnmt1em2Jiemw/Dnmt1+ | ||||||
| Dnmt1tm1Okan/Dnmt1tm2Enl | ||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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